The following is a list of selected publications.

58. "Destabilizing domains derived from the human estrogen receptor." Y Miyazaki, H Imoto, L-c Chen, TJ Wandless J. Am. Chem. Soc. 2012, 134, 3942-3945. (PMID: 22332638)

57. "Imaging the impact of chemically inducible proteins on cellular dynamics in vivo." HS Leong, MM Lizardo, A Ablack, VA McPherson, TJ Wandless, AF Chambers, JD Lewis PLoS One 2012, 7, e30177. (PMID: 22276156)

56. "Ligand-switchable substrates for the ubiquitin-proteasome system." EL Egeler, LM Urner, R Rakhit, C Liu, TJ Wandless J. Biol. Chem. 2011, 286, 31328-31336. Abstract.

55. "Evaluation of FKBP and DHFR based destabilizing domains in Saccharomyces cerevisiae." R Rakhit, SR Edwards, M Iwamoto, TJ Wandless Bioorg. Med. Chem. Lett. 2011, 21, 4965-4968. Abstract.

54. "Small molecule displacement of a cryptic degron causes conditional protein degradation." KM Bonger, L-c Chen, CW Liu, TJ Wandless Nature Chemical Biology 2011, 7, 531-537. Abstract .

53. "Asparagine repeat function in a Plasmodium falciparum protein assessed via a regulatable fluorescent affinity tag." Muralidharan, V.; Oksman, A.; Iwamoto, M.; Wandless, T. J.; Goldberg, D. E. Proc. Natl. Acad. Sci. USA 2011, 108, 4411-4416 Abstract .

52. "Chemical control of FGF-2 release for promoting calvarial healing with adipose stem cells." Kwan, M. D.; Sellmyer, M. A.; Quarto, N.; Ho, A. M.; Wandless, T. J.; Longaker, M. T. J. Biol. Chem. 2011, 286, 11307-11313. Abstract

51. "A general chemical method to regulate protein stability in the mammalian central nervous system." Iwamoto, M.; Björklund, T.; Lundberg, C.; Kirik, D.; Wandless, T. J. Chemistry & Biology, 2010, 17, 981-988. Abstract

50. "A plant-like kinase in Plasmodium falciparum regulates parasite egress from erythrocytes." Dvorin, J. D., Martyn, D. C., Patel, S. D., Grimley, J. S., Collins, C. R., Hopp, C. S., Bright, A. T., Westenberger, S., Winzeler, E., Blackman, M. J., Baker, D. A., Wandless, T. J., Durasingh, M. T. Science 2010, 328, 910-912. Abstract

49. "Dicistronic regulation of fluorescent proteins in the budding yeast Saccharomyces cerevisiae." Edwards, S. R., Wandless, T. J. Yeast 2010, 27, 229-236. Abstract

48. "A general method for conditional regulation of protein stability in living animals." Sellmyer, M.A., Thorne, S. H., Banaszynski, L. A., Contag, C. H., and Wandless, T. J. CSH Protocols 2009 doi: 10.1101/pdb.prot5173. PDF

47. "Regulating protein stability in mammalian cells using small molecules." Hagan, E. L., Banaszynski, L. A., Chen, L.-C., Maynard-Smith, L. A., and Wandless, T. J. CSH Protocols 2009 doi: 10.1101/pdb.prot5172. PDF

46. "The proteasome makes sense of mixed signals." Wandless, T. J. Nat. Chem. Biol., 2009, 5, 3-4.

45. "Recent progress with FKBP-derived destabilizing domains." Chu BW, Banaszynski LA, Chen LC, Wandless TJ. Bioorg Med Chem Lett., 2008 Sep 12. [PubMed]

44. "Chemical control of protein stability and function in living animals." Banaszynski, L. A.; Sellmyer, M. A.; Contag, C. H.; Wandless, T. J.; Thorne, S. H., Nature Medicine, 2008, (14)10, 1123-1127. PDF

43. "Synthesis and Analysis of Stabilizing Ligands for FKBP-Derived Destabilizing Domains." Grimley, J. S.; Chen, D. A.; Banaszynski, L. A.; Wandless, T. J. Bioorg. Med. Chem. Lett., 2008, 18, 759-761. PDF

42. "Rapid Control of Protein Levels in the Apicomplexan Parasite Toxoplasma gondii." Herm-Gotz, A.; Agop-Nersesian, C.; Munter, S.; Grimley, J. S.; Wandless, T. J.; Frischknecht, F.; Meissner, M.  Nature Methods, 2007, 4, 1003-1005. PDF

41. "The Enantioselective Synthesis of Phomopsin B." Grimley, J. S.; Sawayama, A. M.; Tanaka, H.; Stohlmeyer, M. M.; Woiwode, T. F.; Wandless, T. J.  Angew. Chem. Int. Ed., 2007, 46, 8157-8159. PDF

40. "A Directed Approach for Engineering Conditional Protein Stability using Biologically Silent Small Molecules." Maynard-Smith, L. A.; Chen, L.-C.; Banaszynski, L. A.; Ooi, A. G. L.; Wandless, T. J.  J. Biol. Chem., 2007, 282, 24866-24872. PDF

39. "Rescue of Degradation-Prone Mutants of the FK506-Rapamycin Binding (FRB) Protein with Chemical Ligands." Stankunas, K.; Bayle, J. H.; Havranek, J. J.; Wandless, T. J.; Baker, D.; Crabtree, G. R.; Gestwicki, J. E.  ChemBioChem, 2007, 8, 1162-1169. PDF

38. "The Rapamycin-Binding Domain of mTOR is a Destabilizing Domain." Edwards, S. R.; Wandless, T. J.  J. Biol. Chem.  2007, 282, 13395-13401. PDF

37. "Engineering Small Molecule Specificity in Nearly Identical Cellular Environments." Sellmyer, M. A.; Stankunas, K.; Briesewitz, R.; Crabtree, G. R.; Wandless, T. J.  Bioorg. Med. Chem. Lett., 2007, 17, 2703-2705. PDF

36. "SIK1 is a Class II HDAC Kinase that Promotes Survival of Skeletal Myocytes." Berdeaux, R.; Goebel, N., Banaszynski, L, A.; Takemori, H.; Wandless, T. J.; Shelton, G. D.; Montminy, M.  Nature Medicine, 2007, 13, 597-603. PDF

35. "Plasma membrane dissociation of Ras superfamily small GTPases triggered by chemically-induced depletion of phosphoinositide lipid second messengers." Heo, W. D.; Inoue, T.; Park, W. S.; Kim, M. L.; Park, B. O.; Wandless, T. J.; Meyer, T.  Science, 2006, 314, 1458-1461. PDF

34. "A Rapid, Reversible, and Tunable Method to Regulate Protein Function in Living Cells Using Synthetic Small Molecules." Banaszynski, L. A.; Chen, L.-C.; Maynard-Smith, L. A.; Ooi, A. G. L.; Wandless, T. J.  Cell, 2006, 126, 995-1004. PDF

33. "Rapamycin Analogs with Differential Binding Specificity Permit Orthogonal Control of Protein Activity." Bayle, J.H.; Grimley, J.S.; Stankunas, K.; Gestwicki, J .E.; Wandless, T.J.; Crabtree, G. R. Chemistry & Biology, 2006, 13, 99-107. PDF

32. "Conditional Control of Protein Function." Banaszynski, L. A.; Wandless, T. J. Chemistry & Biology, 2006, 13, 11-21. PDF

31. "A Cell-Permeable Activity-Based Probe for Protein and Lipid Kinases." Yee, M. C.; Fas, S.C.; Stohlmeyer, M. M.; Wandless, T. J.; Cimprich, K. A. J. Biol. Chem., 2005, 280, 29053-29059. PDF

30. "Inducible translocation strategy to rapidly activate and inhibit small GTPase signaling pathways." Inoue, T.; Heo, W.D.; Grimley, J.S.; Wandless, T. J.; Meyer, T. Nature Methods, 2005, 2, 415-418. PDF

29. "Characterization of the FKBP•rapamycin•FRB Ternary Complex." Banaszynski, L. A.; Liu, C. W.; Wandless, T. J. J. Am. Chem. Soc., 2005, 127, 4715-4721. PDF

28. "The Total Synthesis of Ustiloxin D and Considerations on the Origin of Selectivity of the Asymmetric Allylic Alkylation." Sawayama, A. M.; Tanaka, H.; Wandless, T. J. J. Org. Chem., 2004, 69, 8810-8820. PDF

27. "Quantitative Analyses of Bifunctional Molecules." Braun, P. D. and Wandless, T. J. Biochemistry, 2004, 43, 5406-5413. PDF

26. "Conditional Protein Alleles Using Knock-in Mice and a Chemical Inducer of Dimerization." Stankunas, K.; Bayle, J. H.; Gestwicki, J. E.; Lin, Y.-M.; Wandless, T. J.; Crabtree, G. R. Mol. Cell, 2003, 12, 1615-1624. PDF

25. "A Bifunctional Molecule That Displays Context-Dependent Cellular Activity." Braun, P. D.; Barglow, K. T.; Lin, Y.-M.; Akompong, T.; Briesewitz, R.; Ray, G. T.; Haldar, K.; Wandless, T. J. J. Am. Chem. Soc., 2003, 125, 7575-7580. PDF

24. "Enantioselective Total Synthesis of Ustiloxin D." Tanaka, H.; Sawayama, A. M.; Wandless, T. J.
J. Am. Chem. Soc., 2003, 125, 6864-6865. PDF

23. "Calcineurin Inhibitors and the Generalization of the Presenter Protein Strategy." Vogel, K. W.; Briesewitz, R.; Wandless, T. J.; Crabtree, G. R. In Advances in Protein Chemistry; E. M. Scolnick, Ed.; Academic Press: San Diego, CA, 2001, 56, 253-291.

22. "Mechanistic Studies of Affinity Modulation." Rosen, M. K.; Amos, C. D.; Wandless, T. J.
J. Am. Chem. Soc., 2000, 122, 11979-11982. PDF

21. "Synthesis of Flavonol Derivatives as Probes of Biological Processes." Tanaka, H.; Stohlmeyer, M. M.; Wandless, T. J.; Taylor, L. P. Tetrahedron Letters, 2000, 41, 9735-9739. PDF

20. "A Confederacy of Bunches: Fundamentals and Applications of a Self-Associating Protein." Wandless, T. J. Proc. Natl. Acad. Sci. USA, 2000, 97, 6921-6923. PDF

19. "Synthesis and Evaluation of Daunorubicin–Paclitaxel Dimers." Kar, A. K.; Braun, P. D.; Wandless, T. J. Bioorg. Med. Chem. Lett., 2000, 10, 261-264. PDF

18. "An Efficient Synthesis of β,γ-Dehydrovaline." Woiwode, T. F.; Wandless, T. J. J. Org. Chem. 1999, 64, 7670-7674. PDF

17. "A Stereospecific Elimination to Form Dehydroamino Acids: Synthesis of the Phomopsin Tripeptide Sidechain." Stohlmeyer, M. M.; Tanaka, H.; Wandless, T. J. J. Am. Chem. Soc., 1999, 121, 6100-6101. PDF

16. "Affinity Modulation of Small-Molecule Ligands by Borrowing Endogenous Protein Surfaces." Briesewitz, R.; Ray, G. T.; Wandless, T. J.; Crabtree, G. R. Proc. Natl. Acad. Sci. USA, 1999, 96, 1953-1958. PDF

15. "A Simple and Efficient Method for the Preparation of Hindered Alkyl–Aryl Ethers." Woiwode, T. F.; Rose, C.; Wandless, T. J. J. Org. Chem. 1998, 63, 9594-9596. PDF

14. "SH2 Domains: A Question of Independence." Wandless, T. J. Curr. Biol. 1996, 6, 125-127.PDF